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Detection of Aluminium-reactive T-lymphocytes in Patients With Vaccination Granulomas

NCT06130462 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2023-11-14

No results posted yet for this study

Summary

Vaccines and subcutanoeus immunotherapy vaccines often contains aluminium, and may induce itching granulomas at the injection site. This is usually diagnosed by patch testing. Another way of detecting metal allergy is by investigation metal-specific cells in the blood.

We include participants both with and without granulomas, all have a blood test taken where we investigate if any participants have aluminium-specific cirkulation cells, and whether we can detect a difference between participants with and without granulomas.

Conditions

  • Granuloma
  • Aluminum Allergy

Interventions

DIAGNOSTIC_TEST

Aluminum

Different concentrations of aluminium added to the blood test in vitro

DIAGNOSTIC_TEST

Tetanus toxoid

Used as control substance

Sponsors & Collaborators

  • National Allergy Research Center, Denmark

    lead OTHER

Principal Investigators

  • Lars Blom, PhD · Allergy clinic, Gentofte Hospital

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-09-13
Primary Completion
2022-10-24
Completion
2023-02-20

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06130462 on ClinicalTrials.gov