MedTrace Logo

Evaluating for Contact Allergies in Patients With Chronic Urticaria

NCT00868036 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 23

Last updated 2019-09-11

No results posted yet for this study

Summary

Hives affects 10-25% of the population worldwide at some time during their lifetime. Hives are itchy transient swellings of the skin lasting 4-36 hours. Chronic urticaria is defined as hives that have been ongoing for six weeks or more.

Patch testing is performed to diagnose allergic contact dermatitis, and if contact allergens are found via patch testing, patients can often be cured of their dermatitis. However, patch testing is currently not routinely performed in the evaluation of patients with chronic idiopathic urticaria.

Our hypothesis is to see if contact allergens can be identified with patch testing in patients with chronic urticaria, and, if any allergens are identified, to see if avoiding these contact allergens will make the chronic urticaria go away.

Conditions

  • Urticaria
  • Patch Testing
  • Dermatitis
  • Allergy
  • Contact Sensitization

Interventions

PROCEDURE

Patch Testing

Patch testing will be performed with a modified North American Contact Dermatitis Group (NACDG) standard series, cosmetics/preservative, fragrance, and textile series in all patients. Based on patient history, other appropriate allergen series will be added. After two days, patches will be removed and the areas will be inspected for type IV hypersensitivity reactions including papules, edema or vesicles. Results will be graded and interpreted at a "delayed read," 3-4 days after allergens are placed with patch testing.

Sponsors & Collaborators

  • American Contact Dermatitis Society (ACDS)

    collaborator OTHER

  • Tufts Medical Center

    lead OTHER

Principal Investigators

  • Pamela Scheinman, M.D. · Tufts Medical Center, Department of Dermatology

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-12-31
Primary Completion
2010-12-31
Completion
2011-01-31

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00868036 on ClinicalTrials.gov