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Immune Reactions in Contact Dermatitis Affected Skin

NCT01546298 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 9

Last updated 2018-06-20

No results posted yet for this study

Summary

This study hopes to improve the investigators understanding of how the immune system acts in allergic contact dermatitis. In order to reach this goal, normal volunteers, who are suspected of having allergic contact dermatitis, will be patch tested for the fifteen most common allergens. Then, biopsies will be taken of the skin at the sites where the there is a positive reaction to the allergen. Also, small biopsies will be taken from an area that received a patch but no allergen and an area that did not receive a patch to serve as controls. In a second stage of the study, volunteers will receive patches with the allergen to which they demonstrated an allergic response. More biopsies will be taken, over three designated time points. The biopsied skin samples will then be studied in a laboratory.

Conditions

  • Allergic Contact Dermatitis

Interventions

OTHER

Patch tests

Patch tests for allergic reaction

Sponsors & Collaborators

  • Washington University School of Medicine

    collaborator OTHER

  • Tel Aviv University

    collaborator OTHER

  • Rockefeller University

    lead OTHER

Principal Investigators

  • Emma Guttman, MD,PhD · The Rockefeller University

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2012-12-14
Completion
2012-12-14

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01546298 on ClinicalTrials.gov