MedTrace Logo

Assessment of the Increased Risk of Infection Following an Ultratrail

NCT06089174 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 471

Last updated 2026-02-17

No results posted yet for this study

Summary

The increase in the practice of running has encouraged a proliferation of studies evaluating the impact of this sport on health. A number of these studies have looked at the influence of endurance events on the immune system. After prolonged exercise, a systemic inflammatory syndrome sets in, with repercussions for the functioning of the immune system. The number of lymphocytes in the blood is reduced, the function of natural killer (NK) cells is impaired and secretory immunity is impaired. During this period of immunosuppression, often referred to as the 'open window', the host may be more susceptible to micro-organisms that bypass the first line of defence.

The invetigators' hypothesis is therefore that ultratrailers are overexposed to the risk of infection due to immunodepression resulting from practising this sport. In order to support this hypothesis, the investigators would like to look at infectious complications in general and ear-nose and throat episodes (rhinitis, pharyngitis, laryngitis, etc.) in particular, which are the most common infections encountered in primary care, along with urinary tract infections.

Conditions

Interventions

OTHER

Ultra-trail

Questionnaires sent to runners at various pre-race and post-race times (Day3, Day6, Day10, Day14 and Day21)

Sponsors & Collaborators

  • Jean Monnet University

    collaborator OTHER

  • Hôpital Privé de la Loire- Saint Etienne

    collaborator UNKNOWN

  • Centre Hospitalier Universitaire de la Réunion

    lead OTHER

Principal Investigators

  • Nicolas BOUSCAREN, MD · CHU de la Réunion

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-06
Primary Completion
2023-11-14
Completion
2023-11-14

Countries

  • Reunion

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06089174 on ClinicalTrials.gov