MedTrace Logo

Collection of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Laboratory Research Studies

NCT00995891 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 88

Last updated 2019-12-05

No results posted yet for this study

Summary

Background:

\- Laboratory research studies require control samples from healthy volunteers to compare with samples from patients. These studies will help researchers better understand and refine treatments for immune system and inflammatory diseases.

Objective:

\- To obtain blood, urine, buccal (mouth) mucosa, normal tissue and bone marrow samples and/or leukopheresis cells from healthy volunteers.

Eligibility:

\- Healthy individuals at least 8 years of age.

Design:

* Volunteers will be recruited through the Program for Healthy Volunteers, Patient Recruitment and Public Liaison Office, or self-referral through the clinicaltrials.gov Web site.
* Health will be confirmed by a brief history and physical examination and blood work.
* Volunteers 8 years of age and older will provide blood and urine samples using standard procedures. Buccal mucosa samples will be obtained by scraping the insides of both cheeks with a sterile nylon brush.
* Bone marrow samples will be obtained from volunteers 18 years of age and older by taking two aspirates from the posterior iliac crest (an area near the hip).
* Normal tissue samples will be obtained from volunteers 18 years of age and older by taking superficial skin samples (punch biopsies)
* Leukopheresis or lymphapheresis will be performed on volunteers 18 years of age and older to obtain white blood cells for research
* Samples will be assigned a unique code and will be stored until they are no longer of scientific value or the volunteer withdraws consent for their use.

Conditions

  • Healthy Volunteers

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    lead NIH

Principal Investigators

  • Angelique Biancotto, Ph.D. · National Institute of Allergy and Infectious Diseases (NIAID)

Eligibility

Min Age
8 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-09-09
Completion
2018-09-05

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00995891 on ClinicalTrials.gov