Investigation of Immune Disorders and Deficiencies
NCT01981785 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 343
Last updated 2017-04-04
Summary
The immune system is an intricate system comprised of specialized cells, proteins, tissues and organs. Proper functioning is critical to the body's ability to defend itself against harmful pathogens. Immunological disorders and deficiencies are defects in the immune system that lead to abnormal immune responses. Abnormal immune responses could be derived from immune deficiencies, dysregulations or hypersensitivities.
The overall goal of this research study is to identify the mechanisms of primary immune deficiencies and immune disorders at the genetic, cellular and molecular level, using novel analytic techniques to be performed on immune cells derived from blood samples. The knowledge gained from the aims of this study could lead to better diagnostics and identify novel targets for therapeutic interventions.
Conditions
- Primary Immune Deficiencies
- Autoimmune Diseases
- Inflammatory Diseases
- Common Variable Immune Deficiencies
- Hypogammaglobulinemia
Sponsors & Collaborators
-
O & O Alpan LLC
lead OTHER
Principal Investigators
-
Oral Alpan, MD · O & O Alpan LLC
Eligibility
- Min Age
- 1 Day
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-12-31
- Primary Completion
- 2018-12-31
- Completion
- 2018-12-31
Countries
- United States
Study Locations
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