MedTrace Logo

Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.

NCT06075914 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2025-05-14

No results posted yet for this study

Summary

Sleep deprivation is a major problem in military populations. Some major consequences of sleep loss are inability to concentrate, poor work efficiency, and increase in errors during daily tasks. Ketogenic supplementation is speculated to alleviate some sleep deprivation issues via action of ketones. Ketones are small molecules that appear in the blood when following a ketogenic diet or consuming ketone supplements. The goal of this project is to find out if diet and/or ketones can improve sleep deprivation detriments over 5 days of sleep restriction (-50% from habitual sleep).

Conditions

  • Sleep Deprivation
  • Nutritional Intervention

Interventions

OTHER

Ketogenic Intervention

Participants will receive ready-to-eat Ketogenic Diet meals.

OTHER

Mediterranean Intervention

Participants will receive ready-to-eat Mediterranean Diet meals.

DIETARY_SUPPLEMENT

Placebo

Participants will receive twice-daily placebo servings to be consumed once in the morning and once before sleep.

DIETARY_SUPPLEMENT

Ketone Ester

Participants will receive twice-daily ketone ester servings to be consumed once in the morning and once before sleep.

Sponsors & Collaborators

  • Ohio State University

    lead OTHER

Principal Investigators

  • Jeff S Volek, PhD · Ohio State University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-05-01
Primary Completion
2026-06-30
Completion
2026-12-31

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06075914 on ClinicalTrials.gov