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Effects of Partial Sleep Deprivation on Cardiac Output During Cycling

NCT06679543 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-04-28

No results posted yet for this study

Summary

The goal of this clinical trial is to determine if attenuations in cardiac output drive the blunted blood pressure response during cycling exercise following a night of partial sleep deprivation in young healthy adults (%50 females). The secondary outcome is to assess sex differences. The main questions it aims to answer are:

* Do reductions in plasma volume drive reductions in cardiac output and therefore blood pressure during exercise following a night of partial sleep deprivation?
* Do sex differences exist?

Participants will:

* Visit the lab after a night of normal sleep and a night of partial sleep deprivation.
* Keep a daily diary of their sleep and food/beverage intake.
* Perform maximal and submaximal exercise on a cycle ergometer.

Conditions

  • Sleep Deprivation

Interventions

OTHER

Partial sleep deprivation

Participants will be asked to come to the lab for testing after a night of partial sleep deprivation. Participants will be asked to fall asleep at their habitual bedtime but wake up early (\~40% of normal sleep duration).

Sponsors & Collaborators

  • University of Guelph

    lead OTHER

Principal Investigators

  • Julian Bommarito, MSc · University of Guelph

  • Philip Millar, PhD · University of Guelph

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-02
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06679543 on ClinicalTrials.gov