Reducing Circulating Sphingolipid Levels to Optimise Cardiometabolic Health - The SphingoFIT Trial
NCT06024291 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 88
Last updated 2025-05-15
Summary
The purpose of this study is to assess the effects of an 8-week supervised high-intensity interval training (HIIT) program (vs. physical activity recommendations according to current guidelines) on a comprehensive panel of circulating sphingolipids in middle-aged females and males at elevated cardiometabolic risk.
Conditions
- Overweight and Obesity
- Dyslipidemias
- Blood Pressure
- Cardiovascular Diseases
- Metabolic Disease
Interventions
- OTHER
-
8-week HIIT programme
See arm description
- OTHER
-
Physical activity recommendation
See arm description
Sponsors & Collaborators
-
University of Lausanne
collaborator OTHER -
Technical University of Munich
collaborator OTHER -
University of Basel
lead OTHER
Principal Investigators
-
Arno Schmidt-Trucksäss, Prof, MD, MA · Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-09-15
- Primary Completion
- 2025-01-15
- Completion
- 2025-01-15
Countries
- Switzerland
Study Locations
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