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Biomarkers and Mechanisms of Disease Progression and Outcome of Aortic Stenosis in Humans

NCT05851209 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 938

Last updated 2023-05-09

No results posted yet for this study

Summary

Biomarkers and mechanisms in the progression of aortic valve stenosis are sometimes not sufficiently understood. The current project will take into account image morphological and immunological aspects that predict the development of hemodynamically relevant aortic valve stenosis in order to identify high-risk patients and to develop further therapeutic options.

Conditions

  • Aortic Stenosis
  • Imaging
  • Pathogenesis
  • Disease Progression
  • Aortic Valve Calcification
  • Genetics

Sponsors & Collaborators

  • German Research Foundation

    collaborator OTHER

  • University Bonn

    collaborator UNKNOWN

  • University Cologne

    collaborator UNKNOWN

  • Collaborative Research Center

    collaborator UNKNOWN

  • Heinrich-Heine University, Duesseldorf

    lead OTHER

Principal Investigators

  • Malte Kelm, Prof. · Clinic for Cardiology, Pneumology and Angiology at University Hospital Düsseldorf

  • Georg Nickenig, Prof. · University Bonn

  • Stephan Baldus, Prof. · University Cologne

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-07-01
Primary Completion
2026-07-31
Completion
2031-07-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05851209 on ClinicalTrials.gov