Blood Donation Could Improve Insulin Sensitivity
NCT05791968 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 89
Last updated 2025-02-21
Summary
Studies in the literature suggest that people with obesity have an excess of stored iron. There is possibly an inverse relationship between ferritin levels and the actions of insulin on glycemic control. The reduction of stored iron by simply donating blood could result in improvements in glycemic control in people with obesity and prediabetes. We propose, to reduce ferritin levels through a standard donation of a unit of whole blood, and to measure if it positively affects glycemic control.
Conditions
- Ferritin
- Insulin Sensitivity
- Blood Donation
Interventions
- PROCEDURE
-
Whole blood standard donation
Effects of a standard whole blood donation on iron stores and insulin sensitivity.
Sponsors & Collaborators
-
SESCAM Centro Regional de Transfusión Toledo-Guadalajara.
collaborator UNKNOWN -
University of Castilla-La Mancha
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-09-15
- Primary Completion
- 2024-04-30
- Completion
- 2024-07-30
Countries
- Spain
Study Locations
More Related Trials
-
The Effect of Oral Iron Supplements on Insulin and Glucose Metabolism in Overweight and Obese Women
NCT07315282 ·Status: RECRUITING ·Phase: NA
-
Glucose, Brain and Microbiota
NCT03889132 ·Status: COMPLETED
-
Insulin-sensitive Obesity: Lessons From Longitudinal Data
NCT02017210 ·Status: COMPLETED
-
Intermittent Fasting to Improve Insulin Secretion
NCT04607096 ·Status: RECRUITING ·Phase: NA
-
Towards Understanding the Relationship Between Meals and Blood Biomarkers
NCT05295706 ·Status: UNKNOWN ·Phase: NA
-
The Degree, Duration and Frequency of Insulin Resistance in Non-operated Patients With Sepsis
NCT04969159 ·Status: COMPLETED
-
Effect of Fasting Free Fatty Acids and Fasting Glucose on 1st and 2nd Phase Insulin Secretion
NCT03998709 ·Status: WITHDRAWN ·Phase: PHASE4
-
The Impact of Passive Heat Treatment on Glycaemic Response During an Oral Glucose Tolerance Test in Diabetic Patients
NCT05610046 ·Status: UNKNOWN ·Phase: NA
-
Health Effects of Liposuction in Overweight Women With Elevated Insulin Levels, Impaired Glucose Tolerance and/or Type 2 Diabetes
NCT00005760 ·Status: COMPLETED
-
Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance
NCT05165706 ·Status: RECRUITING ·Phase: NA
-
Mechanisms Underlying Metabolic Syndrome in Obesity
NCT00579813 ·Status: COMPLETED ·Phase: PHASE4
-
Fasting-Associated Immune-metabolic Remission of Diabetes
NCT05295160 ·Status: COMPLETED ·Phase: NA
-
Hepatic Insulin Sensitivity and Very Low Density Lipoprotein Triglyceride (VLDL-TG) Kinetics
NCT01205750 ·Status: COMPLETED ·Phase: NA
-
Study of Fat Tissue's Ability to Take up Sugar in the Obese Population
NCT02994459 ·Status: ACTIVE_NOT_RECRUITING
-
Insulin Sensitivity After Breast Cancer
NCT05010356 ·Status: RECRUITING ·Phase: NA
-
Genetic Studies of Insulin and Diabetes
NCT00001987 ·Status: RECRUITING
-
Effect of Weight Loss on Brain Insulin Sensitivity in Humans
NCT02991365 ·Status: RECRUITING ·Phase: NA
-
Identification of New Biomarkers of Insulin Resistance
NCT03362554 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Metabolic Response to Fat and Glucose
NCT02603237 ·Status: COMPLETED ·Phase: NA
-
Conventional and Metabolomic Predictors of Prediabetes & Insulin Resistance
NCT05055219 ·Status: COMPLETED
-
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
NCT05277558 ·Status: RECRUITING
-
Defining the Human Insulin Resistance Molecular Network; SIGNATURE
NCT07255807 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Glycemic Response to Different Food Combinations
NCT05456672 ·Status: COMPLETED ·Phase: NA
-
How Quickly Can the Effects of Excessive Caloric Intake on Insulin Resistance be Reversed?
NCT02505958 ·Status: UNKNOWN ·Phase: NA
-
Investigating Brown Adipose Tissue Activation in Humans
NCT01935791 ·Status: COMPLETED ·Phase: NA