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Multimodal Imaging Assessment of the Inflammatory Atheromatous Plaque

NCT01608516 · Status: RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2024-06-20

No results posted yet for this study

Summary

The present study aims at assessing the ability of 68Ga-NODAGA-RGD PET/CT for the detection of inflammatory atheromatous plaques in the carotid arteries, compared to 18F-FDG PET/CT, MRI and US and to determine the contribution of each imaging technique. Current gold standard for inflammation is histopathology.

Hypothesis : 68Ga-NODAGA-RGD might give a better initial evaluation of patients with atheromatous plaques in the carotid artery eligible for endarterectomy.

Conditions

Interventions

DRUG

68Ga-NODAGA-RGD PET/CT

200 MBq 68 Ga-NODAGA-RGD will be administered i.v. and images centred on the carotid area acquired

Sponsors & Collaborators

  • Swiss Heart Foundation

    collaborator OTHER

  • University of Lausanne Hospitals

    lead OTHER

Principal Investigators

  • John O. Prior, PhD, MD · Lausanne University Hospitals

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-04-30
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01608516 on ClinicalTrials.gov