Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography

NCT02021188 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 42

Last updated 2016-08-24

No results posted yet for this study

Summary

This VISION study aims to investigate the role of inflammation in atherosclerosis using 68Ga- DOTATATE PET, and to validate 68Ga-DOTATATE PET imaging for the detection and quantification of vascular inflammation in the aorta, coronary and carotid arteries. This study will test the hypothesis that in subjects undergoing carotid endarterectomy for symptomatic plaques, there will be a positive correlation between carotid artery 68Ga-DOTATATE PET signal and the underlying degree of carotid inflammation measured by immunohistochemical analysis.

Conditions

Sponsors & Collaborators

Principal Investigators

  • James HF Rudd, PhD, FRCP · University of Cambridge

Eligibility

Min Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-08-31
Primary Completion
2016-08-31
Completion
2016-08-31

Countries

  • United Kingdom

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02021188 on ClinicalTrials.gov