Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography
NCT02021188 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 42
Last updated 2016-08-24
Summary
This VISION study aims to investigate the role of inflammation in atherosclerosis using 68Ga- DOTATATE PET, and to validate 68Ga-DOTATATE PET imaging for the detection and quantification of vascular inflammation in the aorta, coronary and carotid arteries. This study will test the hypothesis that in subjects undergoing carotid endarterectomy for symptomatic plaques, there will be a positive correlation between carotid artery 68Ga-DOTATATE PET signal and the underlying degree of carotid inflammation measured by immunohistochemical analysis.
Conditions
- Atherosclerosis
- Stroke
- Transient Ischemic Attack
- Chronic Stable Angina
- Acute Coronary Syndrome
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
James HF Rudd, PhD, FRCP · University of Cambridge
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-08-31
- Primary Completion
- 2016-08-31
- Completion
- 2016-08-31
Countries
- United Kingdom
Study Locations
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