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Expression of IL-8 Before and After Root Canal Treatment in Patients With Symptomatic Apical Periodontitis

NCT05653947 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2023-01-19

No results posted yet for this study

Summary

This clinical study aimed to Compare the levels of Interleukin 8 before and after root canal treatment in patients with apical periodontitis

* Diagnosis
* Local anesthesia
* Isolation and disinfection of the tooth
* Two-staged access cavity preparation
* Patency of the root canals
* First sample collection using paper points
* Working length determination
* Chemico-mechanical preparation
* After 1 week, isolation, Second sample collection then obturation of the root canals and restoration of the tooth.
* Samples will be stored in (-80 C) freezer till collection of all samples then, quantification will be done using ELISA.

Conditions

  • Apical Periodontitis

Interventions

PROCEDURE

Root canal instrumentation, 2.5% NaOCl irrigation

Root canal instrumentation, 2.5% NaOCl irrigation

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SCREENING
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-03-10
Primary Completion
2022-07-30
Completion
2022-11-25

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05653947 on ClinicalTrials.gov