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Effectiveness of Glycyrrhizin as Intracanal Medication in Root Canal Disinfection and Inflammatory Cytokines

NCT06453304 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2024-07-03

No results posted yet for this study

Summary

The objective of this study is to investigate "clinically" the effectiveness of Glycyrrhizin based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.

Conditions

  • Intracanal Medication

Interventions

DRUG

Calcium Hydroxide

Intracanal medication

DRUG

Leddermix

Intracanal medication

DRUG

Glycirrhizin

Intracanal medication

Sponsors & Collaborators

  • Mansoura University

    lead OTHER

Principal Investigators

  • Amany Badr, Prof · Faculty of Dentistry Mansoura University

  • Youssry Elhawary, Prof · Faculty of Dentistry Mansoura University

  • Ghada Abdelrazik, Dr · Faculty of Dentistry Mansoura University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-03-20
Primary Completion
2024-06-05
Completion
2024-07-10

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06453304 on ClinicalTrials.gov