CRP and PCT as Predictors of Sepsis Cause

NCT05605275 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 81

Last updated 2023-07-18

No results posted yet for this study

Summary

The aim of this retrospective study is to determine the predictive role of serum level of procalcitonin (PCT) and c-reactive protein (CRP) in determining the causative agent of sepsis in surgical intensive care unit (ICU) patients. The main question it aims to answer is: what serum level of PCT and CRP is predictive of gram+ and gram- sepsis in patients with positive blood cultures in the surgical ICU. The study will be retrospective and will include all patients with positive blood cultures who were hospitalized in the surgical ICU of University Hospital Osijek in the period from January 2019 to May 2022.

Conditions

  • Sepsis
  • Gram-Positive Bacteremia
  • Gram-negative Bacteremia

Interventions

DIAGNOSTIC_TEST

PCT levels

All patients will have their serum PCT level recorded on the day of the positive blood culture and in the next three days.

DIAGNOSTIC_TEST

CRP levels

All patients will have their serum CRP level recorded on the day of the positive blood culture and in the next three days.

DIAGNOSTIC_TEST

White blood cell count

All patients will have their white blood cell (WBC) count recorded on the day of the positive blood culture and in the next three days.

DIAGNOSTIC_TEST

Platelet count

All patients will have their platelets count recorded on the day of the positive blood culture and in the next three days.

Sponsors & Collaborators

  • Osijek University Hospital

    lead OTHER

Principal Investigators

  • Nenad Neskovic, PhD · Principal Investigator

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-05
Primary Completion
2023-07-10
Completion
2023-07-10

Countries

  • Croatia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05605275 on ClinicalTrials.gov