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Procalcitonin Monitoring May Decrease Antibiotic Use in the Intensive Care Unit

NCT01085994 · Status: UNKNOWN · Type: OBSERVATIONAL

Last updated 2010-10-07

No results posted yet for this study

Summary

Sepsis is common and is associated with significant mortality, morbidity and health-care costs. Unfortunately, its diagnosis is not straightforward because its signs and symptoms are neither specific nor sensitive; in addition, microbiological cultures lack specificity, sensitivity and are plagued by high turn-around times. Because the delay in the institution of antimicrobial therapy may be deleterious, broad-spectrum antibiotics are widely used in ICU-patients, even when they are not needed. Procalcitonin may not be the long sought for bio-marker to establish the diagnosis of sepsis but may help decrease the duration of the administered antibiotic courses once they are started.

Conditions

Interventions

OTHER

Literature search

Literature search followed by systematic review and meta-analysis

Sponsors & Collaborators

  • University of Athens

    lead OTHER

Principal Investigators

  • Petros Kopterides, MD · University of Athens Medical School

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-01-31
Primary Completion
2010-02-28
Completion
2010-03-31

Countries

  • Greece

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01085994 on ClinicalTrials.gov