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Assessment of the Impact of N-acetylcysteine Supplementation on Physical Performance

NCT05604586 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2022-11-03

No results posted yet for this study

Summary

Study aims to verify the hypothesis:

* N-acetylcysteine (NAC) supplementation improves exercise capacity in people training endurance sports and the effectiveness of this supplementation depends on the polymorphism of genes related to folate and glutathione metabolism.
* NAC supplementation affects the parameters of oxidative stress among women and men training endurance disciplines

Conditions

  • Skeletal Muscle Performance
  • Gene Polymorphisms

Interventions

DIETARY_SUPPLEMENT

N-acetylcysteine

100 women and men supplementing 1200 mg of N-acetylcysteine daily in three equal doses. Supplementation will last for 7 days.

DIETARY_SUPPLEMENT

Placebo

100 women and men supplementing 1200 mg of placebo daily in three equal doses. Supplementation will last for 7 days.

Sponsors & Collaborators

  • Poznan University of Life Sciences

    lead OTHER

Principal Investigators

  • Marcin Sadowski, MSc · Poznań University of Life Science

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-05-01
Primary Completion
2025-03-15
Completion
2025-12-31

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05604586 on ClinicalTrials.gov