MedTrace Logo

NAC Supplementation and Skeletal Muscle Performance

NCT01778309 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2013-01-29

No results posted yet for this study

Summary

In this investigation the investigators utilized NAC administration to foster GSH availability during an 8-day period following eccentric exercise-induced muscle damage in order to test our hypotheses: i) antioxidant supplementation does not disturb performance and adaptations induced by exercise-induced muscle injury and ii) redox status perturbations in skeletal muscle are pivotal for the regulation of muscle' inflammatory response and repair.

Conditions

  • Skeletal Muscle Damage
  • Skeletal Muscle Performance
  • Intgracellular Signaling in Skeletal Muscle
  • Inflammatory Status

Interventions

DIETARY_SUPPLEMENT

n-acetylcysteine supplementation

n-acetylcysteine administration: 20 mg//kg/day, orally, daily for eight days following exercise placebo administration: 500 mL orally, daily for eight days following exercise

Sponsors & Collaborators

  • Democritus University of Thrace

    lead OTHER

Principal Investigators

  • Ioannis F Fatouros, Ph.D. · Democritus University of Thrace, Greece

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-01-31
Primary Completion
2011-09-30
Completion
2012-04-30

Countries

  • Greece

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01778309 on ClinicalTrials.gov