Effect of NMN on Muscle Recovery and Physical Capacity in Healthy Volunteers With Moderate Physical Activity

NCT04664361 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 131

Last updated 2024-01-17

No results posted yet for this study

Summary

The purpose of this study is to evaluate the effect of NMN supplementation (250 and 500 mg/day over 38 days) compared to placebo in healthy volunteers with moderate physical activity on muscle recovery, physical capacity, cardiorespiratory recovery, the perception of the arduousness of the effort, the variation in blood lactate levels before and after physical exercise, the perception of the intensity of post-exercise muscle pain (cramps), the body composition and Nicotinamide-Adenine Mononucleotide (NAD+) level in blood.

Conditions

  • Physical Activity
  • Muscle Recovery

Interventions

DIETARY_SUPPLEMENT

Nicotinamide mononucleotide

Daily supplementation with NMN at 250 and 500 mg for 38 days in total

OTHER

Placebo

Daily supplementation with placebo for 38 days in total

Sponsors & Collaborators

  • CEN Nutriment

    collaborator UNKNOWN
  • Centre d'Expertise de la Performance

    collaborator UNKNOWN
  • LGD

    collaborator INDUSTRY
  • Seneque SA

    lead INDUSTRY

Principal Investigators

  • Nadège PLAZA, MD · CEN Nutriment

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
49 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-03-09
Primary Completion
2022-11-10
Completion
2023-05-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04664361 on ClinicalTrials.gov