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Radioiodine Planar and a SPECT/CT Imaging With Iodine-123 for Evaluation of Follicular Thyroid Nodules Prior to Surgery

NCT05591092 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2

Last updated 2025-04-22

No results posted yet for this study

Summary

This study evaluates radioiodine planar and SPECT/CT imaging with iodine-123 in patients with follicular thyroid nodules prior to surgery. Because biopsy alone is not sufficient to distinguish between malignant follicular thyroid nodules and benign follicular thyroid nodules, patients with follicular thyroid lesions are referred for surgery for further evaluation. A non-invasive imaging method that can accurately determine malignancy in follicular thyroid nodules would be valuable in patient management and could potentially spare patients unnecessary surgery. Planar imagine uses a gamma camera to obtain 2D images and SPECT/CT imaging is a special type of CT scan in which a small amount of a radioactive drug is injected into a vein and a scanner is used to make detailed images of areas inside the body where the radioactive material is taken up by the tumor cells. Radioiodine planar and SPECT/CT imaging may be more accurate in distinguishing between benign follicular thyroid nodules and malignant follicular thyroid nodules to help reduce the need for surgery.

Conditions

  • Thyroid Gland Follicular Carcinoma

Interventions

PROCEDURE

Computed Tomography

Undergo a SPECT/CT scan

RADIATION

Iodine I-123

Given PO

PROCEDURE

Planar Imaging

Undergo planar imaging

PROCEDURE

Single Photon Emission Computed Tomography

Undergo a SPECT/CT scan

Sponsors & Collaborators

Principal Investigators

  • Jolanta M. Durski, MD · Mayo Clinic in Rochester

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-11-10
Primary Completion
2025-01-21
Completion
2025-01-21

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05591092 on ClinicalTrials.gov