Evaluation of Thyroid Stunning From a Diagnostic Dose of I-123
NCT02278198 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2019-10-24
Summary
The purpose of the study is to find out if the small dose of radioiodine, that is used for the dosimetry study on patients with differentiated thyroid cancer, may stun the cancer cells and make the thyroid cancer treatment less effective.
Conditions
- Differentiated Thyroid Cancer
Interventions
- DRUG
-
rhTSH
Intramuscular injections of rhTSH (Thyrogen) will be given on days 1 and 2.
Sponsors & Collaborators
-
University of Colorado, Denver
lead OTHER
Principal Investigators
-
Jennifer Kwak, MD · Department of Radiology
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-11-30
- Primary Completion
- 2019-09-20
- Completion
- 2019-09-20
Countries
- United States
Study Locations
More Related Trials
-
The Safety and Effectiveness of rhTSH in Radioiodine Treatment for Patients With Differentiated Thyroid Cancer.
NCT04447183 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Comparison of the Efficacy and Safety of rhTSH as An Adjunctive Diagnostic Tool in Differentiated Thyroid Cancer Patients Who Had Been Thyroidectomized Vs. Patients Who After Thyroid Hormone Withdrawal
NCT04971473 ·Status: COMPLETED ·Phase: PHASE3
-
Iodine I-131 With or Without Selumetinib in Treating Patients With Recurrent or Metastatic Thyroid Cancer
NCT02393690 ·Status: COMPLETED ·Phase: PHASE2
-
Differentiated Thyroid Cancer Patients Treated With Different Doses of Radioactive Iodine.
NCT06134830 ·Status: NOT_YET_RECRUITING
-
Recombinant Human Thyroid Stimulating Hormone for Radioiodine 131I Treatment
NCT06405217 ·Status: RECRUITING ·Phase: NA
-
Iodine I 131 in Treating Patients With Thyroid Cancer
NCT00416949 ·Status: TERMINATED ·Phase: NA
-
High Dose vs Low Dose I 131 +/- rhTSH for Differentiated Thyroid Cancer
NCT00415233 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Clinical Trial of Dose-tolerance, Pharmacokinetics and Iodine Uptake For rhTSH In Post-thyroidectomized Patients
NCT04137185 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients
NCT03065218 ·Status: TERMINATED ·Phase: PHASE4
-
Comparison of I-124 PET/CT for the Diagnosis of Thyroid Cancer
NCT06961084 ·Status: RECRUITING ·Phase: PHASE2
-
Comparison of I-124 and I-131 Radiopharmacokinetics in DTC Patients With Thyroid Hormone Withdrawal
NCT02947399 ·Status: TERMINATED ·Phase: NA
-
Hyperthyroid Follow-Up Study
NCT02989103 ·Status: COMPLETED
-
OnT4-Thyroglobulin Assay Before rhTSH-Aided Radioiodine Ablation
NCT00439127 ·Status: COMPLETED
-
Comparison of the Safety and Successful Ablation of Thyroid Remnant in Post-thyroidectomized Euthyroid Patients (i.e. Patients Administered Thyrogen) Versus Hypothyroid Patients (no Thyrogen) Following 131I Administration
NCT00196729 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment Efficacy and Safety of Low-dose Radioiodine Ablation for Intermediate-risk Differentiated Thyroid Carcinoma
NCT04354324 ·Status: RECRUITING ·Phase: NA
-
Testing a Web-based Intervention for Radioactive Iodine Symptom Management to Improve Health-related Quality of Life Among Differentiated Thyroid Cancer Patients
NCT06853925 ·Status: RECRUITING ·Phase: NA
-
Efficacy of Radium 223 in Radioactive Iodine Refractory Bone Metastases From Differentiated Thyroid Cancer
NCT02390934 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Collect Information About the Use of Redifferentiating Medications as a Standard Treatment for Thyroid Cancer
NCT05733013 ·Status: RECRUITING
-
Efficacy and Safety Study of rhTSH for Adjuvant Radioiodine Ablation Therapy in Patients With Differentiated Thyroid Cancer
NCT04964284 ·Status: RECRUITING ·Phase: PHASE3
-
Evaluation Study of L-T3 Utility in the Follow-up of Patients With Thyroid Cancer
NCT00223158 ·Status: COMPLETED ·Phase: NA
-
Does Radioiodine Treatment Prevent Atrial Fibrillation and Bone Loss in Endogenous Subclinical Hyperthyroidism?
NCT00151723 ·Status: UNKNOWN ·Phase: NA
-
Comparison of Dosimetry After rhTSH or Withdrawal of Thyroid Hormone in Metastatic or Locally Advanced Thyroid Cancer
NCT01403324 ·Status: TERMINATED ·Phase: NA
-
Medico-Economic Comparison of Four Strategies of Radioiodine Ablation in Thyroid Carcinoma Patients
NCT00435851 ·Status: UNKNOWN ·Phase: PHASE3
-
Renal Tracer Elimination in Thyroid Cancer Patients Treated With 131-Iodine
NCT02773667 ·Status: COMPLETED
-
Radioiodine Planar and a SPECT/CT Imaging With Iodine-123 for Evaluation of Follicular Thyroid Nodules Prior to Surgery
NCT05591092 ·Status: COMPLETED