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2-year Caries Clinical Study: Arginine Fluoride-Free Toothpastes vs. NaF Toothpaste

NCT05560945 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 6000

Last updated 2022-10-03

No results posted yet for this study

Summary

The objective of this study is to evaluate the anticaries efficacy for three dentifrices (1.5% arginine in a calcium base, 8.0% arginine in a calcium base, and 0.32% sodium fluoride in a silica base) in a two-year caries clinical study

Conditions

  • Dental Caries

Interventions

DRUG

0.32% Sodium Fluoride Dentifrice Toothpaste

Toothpaste

DRUG

1.5% Arginine Dentifrice

Toothpaste

DRUG

8.0% Arginine Dentifrice

Toothpaste

Sponsors & Collaborators

  • Colgate Palmolive

    lead INDUSTRY

Principal Investigators

  • Yun Po E Zhang, PhD, DDS(Hons) · Colgate Palmolive

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
10 Years
Max Age
14 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-04-15
Primary Completion
2022-03-12
Completion
2022-03-12

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05560945 on ClinicalTrials.gov