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Reduction of Dentine Hypersensitivity Using 8% Arginine Based Toothpaste and 8% Strontium Acetate Based Toothpaste (DH)

NCT03061383 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 51

Last updated 2017-02-23

No results posted yet for this study

Summary

This is a randomized, triple-blind, placebo-controlled study. 51 subjects with a confirmed diagnosis of dentin hypersensitivity were randomized to one of three treatments: Arginine based toothpaste, strontium acetate based toothpaste , or placebo. Treatment will be done at baseline then patients will use the toothpaste at home twice per day by using soft bristled tooth brush and the given dentifrice using modified stillmans method as explained by examiner. Standard test stimuli is calibrated short blast of air syringe, will be applied to sensitive dentin surfaces. Subjects recorded the intensity of sensitivity in response to stimulus on a visual analog scale at baseline, and after 1 week, 2 weeks and 3 months.

Conditions

  • Dentin Hypersensitivity

Interventions

OTHER

8% Arginine based toothpaste

toothpaste

OTHER

8% strontium acetate based toothpaste

toothpaste

OTHER

placebo

toothpaste

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • mohamed adel ezzat khairy, PHD · Professor of Conservative Dentistry, Faculty of Oral and Dental Medicine, Cairo University

  • Maha abdel salam El-baz, PHD · Lecturer of Conservative Dentistry, Faculty of Oral and Dental Medicine, Cairo University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-03-03
Primary Completion
2018-10-03
Completion
2018-11-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03061383 on ClinicalTrials.gov