Association of PeRiODontal Disease and gUt Microbiome With Coronary artEry Disease (PRODUCE Study)
NCT05560087 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 450
Last updated 2025-01-01
Summary
The purpose of this study is to explore the relationship between periodontal disease and coronary artery disease through changes in the gut microbiome. In addition, the investigators aim to find possible periodontal pathogens that have association with cardiovascular disease.
Conditions
- Periodontitis
- Coronary Heart Disease
- Human Microbiome
- Dysbiosis
Sponsors & Collaborators
-
Yonsei University
lead OTHER
Principal Investigators
-
Jong-Won Ha · Severance Hospital
Eligibility
- Min Age
- 19 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-07-01
- Primary Completion
- 2024-12-05
- Completion
- 2024-12-05
Countries
- South Korea
Study Locations
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