Periodontal Therapy in Coronary Artery Patients

Summary

Gingival inflammation has been associated with cardiovascular diseases, including heart attack and stroke, because of elevation of blood risk markers such as cholesterol, glucose and C reactive protein. The treatment of gingival diseases decreases the concentration of these risk factors in the blood of cardiovascular patients.

Conditions

• Cardiovascular Diseases
• Atheroma
• Coronary Artery Disease

Interventions

DEVICE

Subgingival scaling and root planing

Oral hygiene instruction and motivation will be provided altogether with scaling and root planing of all teeth affected by periodontitis under local anesthesia

DEVICE

Oral prophylaxis

One session of supraginigval calculus removal

Sponsors & Collaborators

• Federal University of Rio Grande do Sul

  lead OTHER

Principal Investigators

• Alex N Haas, PhD · Federal University of Rio Grande do Sul, Periodontology

• Cassiano K Rosing, PhD · Federal University of Rio Grande do Sul, Periodontology

• Carisi Polanczyk, PhD · Federal University of Rio Grande do Sul, Cardiology

• Eneida RR Rabelo da Silva, PhD · Federal University of Rio Grande do Sul

• Marco A Saffi, MS · Federal University of Rio Grande do Sul, Cardiology

• Cassio Kampits, MS · Federal University of Rio Grande do Sul, Periodontology

• Ingrid Sanada, MS · Federal University of Rio Grande do Sul, Periodontology

• Marlon Montenegro, MS · Federal University of Rio Grande do Sul, Periodontology

• Mariana V Furtado, MS · Federal University of Rio Grande do Sul, Cardiology

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

35 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2012-01-31

Primary Completion

2016-07-31

Completion

2017-12-31

Countries

• Brazil

Study Locations