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Assessment of Fluid Responsiveness in Septic Shock Patients, Can End-tidal co2 Measurement Help?

NCT05557461 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2023-01-25

No results posted yet for this study

Summary

Fluid therapy is important in patients with sepsis and septic shock. There are many invasive and non-invasive methods to assess fluid responsiveness in patients. The specificities and sensitivities of these methods are highly variable. The reason for our study was to determine end-tidal co2 and fluid responsiveness in septic shock patients. The aim of the study was to evaluate the fluid response using the End-tidal CO2 difference in septic shock patients receiving intubated mechanical ventilation support.

Conditions

  • Septic Shock
  • Hypovolemia
  • Sepsis

Interventions

DEVICE

End-tifdal co2, systolic, diastolic blood pressure, ppv values and vci distensibility

(0,1,3,5 minutes measurements will be taken) measured before and after the test will be recorded and compared. Cardiac output and stroke volume variation, vci distensibility will be measured and recorded by a specialist cardiologist using siemens ocuson cv70 (Siemens AG Medical Solutions, Henkestrasse, the Germany) echocardiography before and after the test.

Sponsors & Collaborators

  • Bozyaka Training and Research Hospital

    lead OTHER

Principal Investigators

  • Zeki T Tekgül, Assoc Prof · Izmir Bozyaka Training and Research Hospital

  • Özkan özmuk, MD · Izmir Bozyaka Training and Research Hospital

  • Çağrı Yeşilnacar, MD · Izmir Bozyaka Training and Research Hospital

  • Oğuz Uçar, MD · Izmir Bozyaka Training and Research Hospital

  • Mehmet Uğur Bilgin, MD · Izmir Bozyaka Training and Research Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-09-20
Primary Completion
2023-02-27
Completion
2023-03-30

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05557461 on ClinicalTrials.gov