ACHIEVE Brain Health Follow-Up Study

Summary

The ACHIEVE Brain Health Follow-Up Study is a 3-year follow-up to the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) randomized study to determine the long-term effect of hearing intervention vs. successful aging/delayed hearing intervention on rates of cognitive decline and incident mild cognitive impairment or dementia.

Conditions

• Aging
• Cognitive Decline
• Mild Cognitive Impairment
• Dementia
• Hearing Loss

Interventions

OTHER

Hearing intervention

The hearing intervention is best practices hearing rehabilitation treatment program, consisting of fitting with hearing aids and other hearing assistive technologies along with comprehensive, individualized hearing rehabilitation sessions with a study audiologist spaced over the 2-3 months post-fitting designed to provide all the active components of the intervention. Participants also received semi-annual booster sessions with the study audiologist for 3 years and will continue to receive hearing healthcare from the study audiologist and complete semi-annual sessions for 3 additional years.

OTHER

Successful aging/delayed hearing intervention

The successful aging health education program follows the protocol and materials developed for the 10 Keys to Healthy Aging program. The program involved individualized sessions with a study health educator, with initial sessions spaced over the 2-3 months post-randomization and semi-annual sessions for 3 years. Upon completion of the ACHIEVE trial, these participants are offered the best practices hearing rehabilitative treatment program with comprehensive, individualized sessions post-fitting and will receive semi-annual booster sessions with the study audiologist for 3 years.

Sponsors & Collaborators

• University of North Carolina

  collaborator OTHER

• University of South Florida

  collaborator OTHER

• University of Minnesota

  collaborator OTHER

• University of Mississippi Medical Center

  collaborator OTHER

• Wake Forest University

  collaborator OTHER

• Mayo Clinic

  collaborator OTHER

• National Institute on Aging (NIA)

  collaborator NIH

• NYU Langone Health

  collaborator OTHER

• Johns Hopkins University

  lead OTHER

Principal Investigators

• Frank R Lin, MD, PhD · Johns Hopkins University

• Josef Coresh, MD, PhD · NYU Langone Health

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

73 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-01-12

Primary Completion

2026-06-30

Completion

2026-06-30

Countries

• United States

Study Locations