MedTrace Logo

Assessment of the Hemodynamic Effects of PEEP According to Alveolar Recruitment During the ARDS

NCT05524558 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2022-09-01

No results posted yet for this study

Summary

The corner stone of the treatment of ARDS is mechanical ventilation with high levels of positive end-expiratory pressure, also called PEEP. A high level of PEEP is recommended and frequently used. But PEEP can lower cardiac output and contribute to circulatory failure during mechanical ventilation. Nevertheless, in theory, the PEEP-induced pulmonary vascular resistance (PVR) increase could depend on the level of alveolar recruitment, but it has never been proven. Thus, the aim of this study is to determine the relation between the high-PEEP induced PVR and the alveolar recruitment or overdistension.

Conditions

  • ARDS, Human
  • Ventilation Therapy; Complications
  • Alveolar; Disorder

Interventions

DEVICE

Pulmonary artery catheter

PAC already in place

DEVICE

Esophagal pressure

Esophagal pressure already in place

Sponsors & Collaborators

  • Bicetre Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-02-01
Primary Completion
2022-09-30
Completion
2022-11-30

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05524558 on ClinicalTrials.gov