Optimization of Arterial Oxygen Transport by Positive End-expiratory Pressure Variation in Acute Respiratory Distress Syndrome
NCT01256333 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12
Last updated 2013-07-03
Summary
Despite improving in the treatment of acute respiratory distress syndrome (ARDS), this affection keep an elevate rate of death. The strategy of mechanical ventilation is more and more under definite protocol, following large strength randomized studies. Although, it doesn't exist today element allowing to adjust the level of Positive End-Expiratory Pressure (PEEP) with improvement in patient's survival.
The investigators proposed in this study to determinate the level of PEEP adjust to obtain the better arterial oxygen transport (TaO2). The investigators going to conduct a physiologic, observational, none controlled study. All patients hospitalized in intensive care unit of Pontchaillou hospital with ARDS criteria and without specific exclusion criteria will be included. Primary objective is to looking for the optimum level of PEEP for TaO2.
Conditions
- Respiratory Distress Syndrome, Adult
Sponsors & Collaborators
-
Rennes University Hospital
lead OTHER
Principal Investigators
-
Loic Chimot · CH de Périgueux
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-01-31
Countries
- France
Study Locations
More Related Trials
-
Hemodynamic and Cardiac Effects of Individualized PEEP Titration Using Esophageal Pressure Measurements in ARDS Patients
NCT02617914 ·Status: WITHDRAWN
-
Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients
NCT03202641 ·Status: TERMINATED ·Phase: NA
-
Contribution of Transthoracic and Transcranial Ultrasonography to the Titration of PEEP in Patients With ARDS and ABI
NCT07248995 ·Status: RECRUITING ·Phase: NA
-
Trans-pulmonary Pressure in ARDS
NCT02416037 ·Status: COMPLETED ·Phase: NA
-
Lung Imaging for Ventilatory Setting in ARDS
NCT02149589 ·Status: COMPLETED ·Phase: NA
-
Effect of Initial Empirical PEEP Setting on the Esophageal Pressure-guided PEEP Titration in ARDS
NCT05442073 ·Status: COMPLETED
-
Transpulmonary Pressure in Right Ventricle Protection of ARDS
NCT05629832 ·Status: COMPLETED ·Phase: NA
-
Influence Positive End-expiratory Pressure on Autoregulation in Patients With Respiratory Insufficiency
NCT01376518 ·Status: COMPLETED
-
The Value of Combined Critical Care Ultrasound and PAC Monitor Oriented Therapy Protocol to Patients of ARDS With ACP
NCT03971331 ·Status: UNKNOWN ·Phase: NA
-
Mechanical Ventilation-induced Acute Kidney Injury [AKI]
NCT06638255 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Evaluation of Airway Pressure Release Ventilation in COVID-19 ARDS
NCT04386369 ·Status: COMPLETED
-
Effect of Prone Positioning on Mortality in Patients With Mild to Moderate Acute Respiratory Distress Syndrome.
NCT05056090 ·Status: UNKNOWN ·Phase: NA
-
Position and Esophageal Pressure
NCT02816359 ·Status: COMPLETED ·Phase: NA
-
The Effect of Positive End-Expiratory Pressure on Functional Residual Capacity During Mechanical Ventilation
NCT03511651 ·Status: UNKNOWN ·Phase: NA
-
Comparison of PEEP in Acute Decompensated Heart Failure
NCT04853563 ·Status: UNKNOWN ·Phase: NA
-
Changes in Cerebral Oxygenation During the Prone Position in Patients With Acute Respiratory Distress Syndrome
NCT02415738 ·Status: COMPLETED
-
Ventilatory Influence on Cerebral Oxygenation During VATS
NCT05033353 ·Status: COMPLETED ·Phase: NA
-
Association Between Driving Transpulmonary Pressure and Extravascular Lung Water in Patients with ARDS
NCT05474196 ·Status: RECRUITING
-
Effects of Ventilation With Tidal Volume Adjusted on Driving Pressure on Ventilation/Perfusion Ratios and Hemodynamics in ARDS
NCT06817629 ·Status: NOT_YET_RECRUITING
-
Optimization of Positive End Expiratory Pressure by Use of Pulmonary Ultrasound for Patients With Blunt Chest Trauma Treated by Non-Invasive Ventilation (Opti-PEP).
NCT06072339 ·Status: RECRUITING ·Phase: NA
-
Impact of the Transpulmonary Pressure on Right Ventricle Function in Acute Respiratory Distress Syndrome
NCT04184674 ·Status: COMPLETED ·Phase: NA
-
Diaphragm Ultrasound Vs Transpulmonary Pressure To Set PEEP in ARDS
NCT02463773 ·Status: COMPLETED ·Phase: NA
-
Effect of APRV vs. LTV on Right Heart Function in ARDS Patients: a Single-center Randomized Controlled Study
NCT05922631 ·Status: COMPLETED ·Phase: NA
-
A Non-invasive Evaluation of Kidney-Lung Interactions
NCT03747731 ·Status: UNKNOWN
-
Physiological Studies in the Prone Position in Patients With ARDS
NCT06586736 ·Status: RECRUITING