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Specific Mechanical Power Assessment in Patients With Acute Respiratory Distress Syndrome

NCT05410262 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 18

Last updated 2023-03-07

No results posted yet for this study

Summary

In ARDS patients, mechanical ventilation should minimize ventilator-induced lung injury. The mechanical power which is the energy per unit time released to the respiratory system according to the applied tidal volume, PEEP, respiratory rate, and flow should reflect the ventilator-induced lung injury

Conditions

  • Ventilation, Mechanical

Interventions

OTHER

Evaluation of CT images

A helicoidal CT scanner will be used (Aquilion CXL, Toshiba, Japan), with AIDR 3D technique (Adaptive Iterative Dose Reduction 3D) in order to minimize exposure to X-rays. Two complete thorax CT scans will be performed, one of them in expiratory pause (PEEP) and the other in inspiratory pause (PPlat). Esophageal pressure shall be measured (FluxMed GrT, Argentina) and transpulmonary pressure will be calculated at the end of inspiration (Ppl-insp) and expiration (Ppl-exp).

Sponsors & Collaborators

  • Hospital El Cruce

    lead OTHER

Principal Investigators

  • Nestor Pistillo · Hospital El Cruce

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-07-01
Primary Completion
2022-11-30
Completion
2022-12-30

Countries

  • Argentina

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05410262 on ClinicalTrials.gov