Effects of Heart Control at Different Stages in Patients of Septic Shock With Tachycardia
NCT05389176 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 96
Last updated 2022-05-25
Summary
A sigle-center, randomized controlled trial will be do to investigate the effects of esomol on heart rate, clinical parameters, mortality, and safety in septic shock patients with tachycardia at different stages, compared with patients who received conventional therapy.
Conditions
- Septic Shock
- Tachycardia
Interventions
- DRUG
-
Esmolol
a continuous esmolol infusion titrated to maintain heart rate between 70/min and 100/min
Sponsors & Collaborators
-
Chinese Medical Association
lead NETWORK
Principal Investigators
-
Wenkui Yu, MD · The Affliated Drum Tower Hospital, Medical School of Nanjing University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-07-01
- Primary Completion
- 2024-03-31
- Completion
- 2024-06-30
More Related Trials
-
Pilot Phase II Study: Hemodynamic Tolerance and Anti-inflammatory Effects of Esmolol During the Treatment of Septic Shock
NCT02120404 ·Status: UNKNOWN ·Phase: PHASE2
-
The Effect of Esmolol on Clinical Prognosis of Patients With Severe Sepsis
NCT02794025 ·Status: COMPLETED ·Phase: NA
-
Esmolol Effects on Heart and Inflammation in Septic Shock
NCT02068287 ·Status: UNKNOWN ·Phase: PHASE2
-
Esmolol Infusion for Patients With Septic Shock and Persistent Tachycardia
NCT02841241 ·Status: COMPLETED ·Phase: PHASE2
-
Intravenous Metoprolol in Septic Shock
NCT06592547 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Dexmedetomidine vs Esmolol or Placebo on Cerebral Hemodynamics in Septic Shock
NCT06169475 ·Status: COMPLETED ·Phase: NA
-
Effect of Heart Rate Control With Ivabradine on Hemodynamic in Patients With Sepsis
NCT05882708 ·Status: RECRUITING ·Phase: PHASE4
-
Effect of a Continuous Infusion of Esmolol on Stroke Volume in Patients With Hyperdynamic Vasoplegic Septic Shock
NCT02609152 ·Status: WITHDRAWN ·Phase: PHASE3
-
The Preventive Effect of Shenfu Injection on Myocardial Dysfunction in Sepsis
NCT06898723 ·Status: RECRUITING ·Phase: PHASE4
-
Rate, Rhythm or Risk Control for New-onset Supraventricular Arrhythmia During Septic Shock: a Randomized Controlled Trial
NCT04844801 ·Status: RECRUITING ·Phase: NA
-
Continuos Terlipressin Infusion in Septic Shock
NCT01697410 ·Status: UNKNOWN ·Phase: NA
-
Use of Dobutamine in Patients With Sepsis and Maintained Hypoperfusion After Initial Volemic Resuscitation.
NCT05953142 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Effect of Ivabradine on Microcirculation and Cardiac Output in Septic Shock Patients
NCT05141071 ·Status: COMPLETED ·Phase: PHASE2
-
Early Goal Directed Sedation on Microcirculation in Septic Shock
NCT02612363 ·Status: UNKNOWN ·Phase: PHASE4
-
Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility
NCT04748796 ·Status: RECRUITING ·Phase: PHASE3
-
Anisodamine Critically Ill SeptIc Shock
NCT02442440 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effect of Norepinephrine Administration on Ventricular Systolic Function in Septic Shock
NCT05355961 ·Status: COMPLETED
-
Shenfu Injection Improves Arterial Vascular Reactivity
NCT03749525 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Esmolol to Control Adrenergic Storm in Septic Shock- ROLL-IN 2
NCT03208257 ·Status: UNKNOWN ·Phase: PHASE2
-
Methylene Blue for the Treatment of Septic Shock
NCT06532240 ·Status: COMPLETED ·Phase: PHASE3
-
Place of Echocardiography in IV Fluid Therapy in Patients With Septic Shock and Left Ventricular Systolic Dysfunction
NCT02899897 ·Status: COMPLETED
-
Initiation of Hydrocortisone for the Treatment of Septic Shock
NCT02580240 ·Status: COMPLETED ·Phase: NA
-
Erythromycin in Septic Patients: Immunomodulatory Role and Clinical Impact
NCT04665089 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Melatonin in Patients With Severe Sepsis or Septic Shock
NCT01858909 ·Status: UNKNOWN ·Phase: PHASE3
-
Protocol-driven Hemodynamic Support for Patients With Septic Shock
NCT00335907 ·Status: UNKNOWN ·Phase: NA