The Effect of Esmolol on Patients With Sepsis
NCT04537767 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120
Last updated 2020-09-03
Summary
The investigators conduct an RCT to explore the efficacy of esmolol in patients with septic shock and sepsis.
Conditions
Interventions
- DRUG
-
Esmolol
The protocol required a titrated esmolol infusion commenced at 25 mg/ h, with an upper dose limit of 2000 mg/h, to maintain the HR between 75 and 90 bpm in ES group. The control group were treated with placebo.
- DRUG
-
Placebo
Sponsors & Collaborators
-
Shanghai Zhongshan Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-10-01
- Primary Completion
- 2023-03-31
- Completion
- 2023-09-30
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