Kidney Precision Medicine Project (KPMP) - COVID-19 Protocol

Summary

Since its inception, KPMP has developed sophisticated protocols for collection and analysis of human kidney tissue, and for collection of biofluids. Members of the consortium have wide-ranging expertise in conducting clinical studies, processing kidney tissue, advanced structural and molecular analysis and complex bioinformatics analysis, which will be used to leverage effectively as a group to better understand kidney disease.

This joint protocol aims to synergize the COVID-19 study efforts of KPMP academic research centers, to collectively study COVID-19, including its renal presentation using kidney tissue and/or biofluids from patients suffering from COVID-19. This will increase the breadth and depth of data available to the public to expedite discoveries, identify therapeutics, and improve outcomes for patients with COVID-19. It will additionally bring the expertise of KPMP investigators to bear against this pandemic.

Conditions

• Acute Kidney Failure
• Acute Kidney Insufficiency
• Acute Renal Failure
• Acute Renal Injury
• Acute Renal Insufficiency
• Kidney Failure, Acute
• Kidney Insufficiency, Acute
• Renal Failure, Acute
• Renal Insufficiency, Acute
• Covid19
• Sars-CoV-2 Infection

Sponsors & Collaborators

• National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

  collaborator NIH

• University of Michigan

  collaborator OTHER

• Icahn School of Medicine at Mount Sinai

  collaborator OTHER

• Broad Institute of MIT and Harvard

  collaborator OTHER

• Indiana University

  collaborator OTHER

• Johns Hopkins University

  collaborator OTHER

• Joslin Diabetes Center

  collaborator OTHER

• Pacific Northwest National Laboratory

  collaborator FED

• Princeton University

  collaborator OTHER

• Stanford University

  collaborator OTHER

• Ohio State University

  collaborator OTHER

• University of California, San Diego

  collaborator OTHER

• University of California, San Francisco

  collaborator OTHER

• The University of Texas Health Science Center at San Antonio

  collaborator OTHER

• University of Texas

  collaborator OTHER

• Washington University School of Medicine

  collaborator OTHER

• Yale University

  collaborator OTHER

• Beth Israel Deaconess Medical Center

  collaborator OTHER

• University of Washington

  lead OTHER

Principal Investigators

• Jonathan Himmelfarb, MD · University of Washington

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-06-15

Primary Completion

2022-06-30

Completion

2022-10-30

Countries

• United States

Study Locations