Procalcitonin and Brain Natriuretic Peptides in Patients With Chronic Kidney Disease.
NCT03698877 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 79
Last updated 2023-10-19
Summary
The study is being conducted to determine if the blood test Brain Natriuretic Protein (BNP) can demonstrate the presence of extra fluid in patients with chronic kidney disease treated by hemodialysis. It will also try to determine the blood test Procalcitonin (PCT) can help identify the cause of the fever, specifically if a fever is caused by a bacterial infection. It will also evaluate whether new blood tests in the future (such as DNA, RNA, metabolite, and protein based tests) can be developed to help predict other complications in patients with chronic kidney disease treated by hemodialysis.
Conditions
- Kidney Failure, Chronic
Interventions
- DIAGNOSTIC_TEST
-
Brain Natriuretic Protein (BNP) and Procalcitonin (PCT) blood tests
For patients with suspected infection, PCT levels will be drawn at the time of suspected infection and again at the start of the next HD treatment. For patients with shortness of breath, PCT and BNP levels will be drawn at the time of the complaint and again at the start of the next HD treatment.
Sponsors & Collaborators
-
Weill Medical College of Cornell University
collaborator OTHER -
The Rogosin Institute
lead OTHER
Principal Investigators
-
Jeffrey Silberzweig, MD · The Rogosin Institute
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-12-26
- Primary Completion
- 2022-04-30
- Completion
- 2022-04-30
Countries
- United States
Study Locations
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