Procalcitonin and Brain Natriuretic Peptides in Patients With Chronic Kidney Disease.

NCT03698877 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 79

Last updated 2023-10-19

No results posted yet for this study

Summary

The study is being conducted to determine if the blood test Brain Natriuretic Protein (BNP) can demonstrate the presence of extra fluid in patients with chronic kidney disease treated by hemodialysis. It will also try to determine the blood test Procalcitonin (PCT) can help identify the cause of the fever, specifically if a fever is caused by a bacterial infection. It will also evaluate whether new blood tests in the future (such as DNA, RNA, metabolite, and protein based tests) can be developed to help predict other complications in patients with chronic kidney disease treated by hemodialysis.

Conditions

  • Kidney Failure, Chronic

Interventions

DIAGNOSTIC_TEST

Brain Natriuretic Protein (BNP) and Procalcitonin (PCT) blood tests

For patients with suspected infection, PCT levels will be drawn at the time of suspected infection and again at the start of the next HD treatment. For patients with shortness of breath, PCT and BNP levels will be drawn at the time of the complaint and again at the start of the next HD treatment.

Sponsors & Collaborators

  • Weill Medical College of Cornell University

    collaborator OTHER
  • The Rogosin Institute

    lead OTHER

Principal Investigators

  • Jeffrey Silberzweig, MD · The Rogosin Institute

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-12-26
Primary Completion
2022-04-30
Completion
2022-04-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03698877 on ClinicalTrials.gov