New genomic studies show a practical recall-by-genotype strategy for psychiatry, shared genetic liability across psychiatric and physical conditions, and improved disease prediction using disease-history trajectories.
Multiple myeloma immunotherapies like bispecific antibodies and CAR-T cells show high response rates and prolonged survival, but access is hindered by the need for initial hospital stays for bispecifics. Research indicates mezigdomide can reverse T cell exhaustion to boost these therapies, while longer-term CARVYKTI data show significant survival benefits.
ASCO 2026 data show CBM588 boosts immunotherapy in kidney cancer and a bispecific combo improves lymphoma. Early-day ICI infusion, mezigdomide T cell reinvigoration, and dostarlimab maintenance also advance cancer immunotherapy.
Cerebral organoids are revealing how Ebola virus persists, aiding treatment research for rare Parkinson's disease, modeling Alzheimer's, and gaining whole-network recording capabilities.
New data from LIBERTY studies show subcutaneous infliximab effectively restored and maintained disease control in Crohn's disease and ulcerative colitis patients after drug holiday of 16 weeks or more, with sustained efficacy through Week 102.
Researchers at Icahn School of Medicine at Mount Sinai found that major depressive disorder shares key immune abnormalities with atopic dermatitis, particularly Th2 pathway activation. The team plans to test dupilumab in a clinical trial for depression.
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RECRUITING | NA |
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NOT_YET_RECRUITING | |
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NOT_YET_RECRUITING | |
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NOT_YET_RECRUITING |
