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Chronotherapy in Children With Chronic Kidney Disease

NCT05353335 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2025-06-13

No results posted yet for this study

Summary

This is a pilot, crossover trial in which the investigator will determine if retiming of one anti-hypertensive medication from morning to evening can effectuate normal blood pressure dipping patterns in children and adolescents with chronic kidney disease.

Conditions

Interventions

OTHER

Re-timing of anti-hypertensive drug

The intervention will consist of shifting the anti-hypertensive medication from morning/early dose to an evening/later dose

OTHER

Current regimen

The participants will begin on their current regimen.

Sponsors & Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    collaborator NIH

  • American Heart Association

    collaborator OTHER

  • Yale University

    lead OTHER

Principal Investigators

  • Christine Bakhoum · Yale University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
6 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-04-30
Primary Completion
2026-02-28
Completion
2026-02-28

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05353335 on ClinicalTrials.gov