A Pilot Study of Chlorthalidone Among Patients With Poorly Controlled Hypertension and CKD
NCT01750294 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 14
Last updated 2016-06-13
Summary
It is estimated that in the United States there are approximately 8 million individuals with moderate to severe chronic kidney disease (CKD), not on dialysis. Volume expansion plays an important role in the pathogenesis of hypertension in patients with CKD. For this pilot study, the investigators hypothesize that administration of chlorthalidone among patients with moderate to severe CKD will improve blood pressure (BP).
Conditions
- Chronic Kidney Disease
- Poorly-Controlled Hypertension
Interventions
- DRUG
-
Chlorthalidone
Sponsors & Collaborators
-
Indiana University
lead OTHER
Principal Investigators
-
Rajiv Agarwal, MD FASN FAHA · Indiana University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-08-31
- Primary Completion
- 2013-08-31
- Completion
- 2013-08-31
Countries
- United States
Study Locations
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