MedTrace Logo

Zona Pellucida Thinning Versus Drilling During Laser-assisted Hatching

NCT05311553 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2022-10-21

No results posted yet for this study

Summary

Two hundred cycles will be enrolled (100 laser-assisted thinning and 100 laser-assisted drillings).

They will be compared regarding the implantation and clinical pregnancy rates

Conditions

Interventions

PROCEDURE

Zona pellucida thinning

Laser-assisted hatching will be conducted using a Laser System with a 1.48-μm diode laser at 300 m W through thinning. The laser thinning will be performed by making 2-3 holes without reaching the inner membrane at a depth of60-80% of the Zona pellucida thickness.

PROCEDURE

Zona pellucida drilling

Laser-assisted hatching will be conducted using a Laser System with a 1.48-μm diode laser at 300 m W through drilling. The laser opening will be made from the outside to the inside of the Zona pellucida.

Sponsors & Collaborators

  • National Research Centre, Egypt

    lead OTHER

Principal Investigators

  • Ahmed Ayoub · National Research Centre, Egypt

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
25 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-01
Primary Completion
2022-12-30
Completion
2022-12-30

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05311553 on ClinicalTrials.gov