Oocyte Activation: Revised or Initial AGT Technique, Which is Better?! A Sibling-oocytes-split Design

NCT05113238 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 222

Last updated 2022-09-21

No results posted yet for this study

Summary

This study will be conducted to compare two different Assisted Gamete treatment (AGT) with oocyte-sibling-split design control group : AGT- initial protocol for activating oocytes by culturing oocytes in calcium ionophore after injection for two rounds of 10 minutes at 37 C, 30 minutes after injection.

sample group : AGT-revised protocol oocytes will be injected by sperm previously cultured in Ca ionophore and 0.4 pL of calcium ionophore then will be cultured in calcium ionophore after injection for 10 minutes

Conditions

  • Assisted Reproductive Technology

Interventions

PROCEDURE

Assisted gamete activation

compare two different assisted gamete activation protocols to improve ICSI outcome

Sponsors & Collaborators

  • Hawaa Fertility Center

    collaborator OTHER
  • Royal Fertility Center, Egypt

    lead OTHER

Principal Investigators

  • Sahar SA Eissa, PHD · research team leader

  • Engy EA Abdallah, M.sc · investigator & researcher

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-10-15
Primary Completion
2021-12-25
Completion
2021-12-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05113238 on ClinicalTrials.gov