Oocyte Activation: Revised or Initial AGT Technique, Which is Better?! A Sibling-oocytes-split Design
NCT05113238 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 222
Last updated 2022-09-21
Summary
This study will be conducted to compare two different Assisted Gamete treatment (AGT) with oocyte-sibling-split design control group : AGT- initial protocol for activating oocytes by culturing oocytes in calcium ionophore after injection for two rounds of 10 minutes at 37 C, 30 minutes after injection.
sample group : AGT-revised protocol oocytes will be injected by sperm previously cultured in Ca ionophore and 0.4 pL of calcium ionophore then will be cultured in calcium ionophore after injection for 10 minutes
Conditions
- Assisted Reproductive Technology
Interventions
- PROCEDURE
-
Assisted gamete activation
compare two different assisted gamete activation protocols to improve ICSI outcome
Sponsors & Collaborators
-
Hawaa Fertility Center
collaborator OTHER -
Royal Fertility Center, Egypt
lead OTHER
Principal Investigators
-
Sahar SA Eissa, PHD · research team leader
-
Engy EA Abdallah, M.sc · investigator & researcher
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-10-15
- Primary Completion
- 2021-12-25
- Completion
- 2021-12-30
Countries
- Egypt
Study Locations
More Related Trials
-
Zona Pellucida Thinning Versus Drilling During Laser-assisted Hatching
NCT05311553 ·Status: UNKNOWN ·Phase: NA
-
Oocyte Cryopreservation: Evaluation of an Oocyte Freezing and Thawing Technique
NCT00713869 ·Status: UNKNOWN
-
Study of the Cleavage of the Egg in Relation to the Stimulation Treatment
NCT01674894 ·Status: COMPLETED
-
Artificial Oocyte Activation Comparing Tow Different Agents
NCT02424214 ·Status: COMPLETED ·Phase: NA
-
Effect of Oocyte Vitrification on Fertilization Rate, Embryo Quality and Development
NCT01422395 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Effectiveness of PGT-A: IVF Versus ICSI
NCT03708991 ·Status: COMPLETED
-
Advanced Sperm Selection Techniques and Their Contribution to Blastocyst Euploidy Rates
NCT05494216 ·Status: COMPLETED ·Phase: NA
-
Comparing Two Types of Endometrial Activation Prior to Embryo Transfer
NCT04363879 ·Status: COMPLETED ·Phase: NA
-
Egg Freezing Pilot Study
NCT00839839 ·Status: COMPLETED ·Phase: NA
-
Co-incubation of Oocytes With Sperm: Defining the Optimal Incubation Time
NCT04627545 ·Status: COMPLETED ·Phase: NA
-
Extended Culture of Day 3 to Day 5 Frozen Thawed Day 3 Embryos Versus Day 5 Frozen-Thawed Embryos
NCT05858333 ·Status: COMPLETED ·Phase: NA
-
Comparative Study to Assess the Ongoing Pregnancy Rate for Poor Responders Women Undergoing Different Embryo Transfer Protocols
NCT05014867 ·Status: COMPLETED
-
Comparison of Transfers of Fresh and Thawed Embryos in Patients With Prior Failed Embryo Transfer Cycles
NCT00736177 ·Status: WITHDRAWN ·Phase: NA
-
Impact of Dry vs Humidified Culture Conditions on Blastocyst Development and Aneuploidy: A Time-lapse Sibling Oocyte Study
NCT07270250 ·Status: RECRUITING ·Phase: NA
-
Timing of COC Denudation and Embryo Quality
NCT03813745 ·Status: UNKNOWN
-
What is the Optimal Cycle Regimen for Frozen- Thawed Embryo Transfer Cycles
NCT03954587 ·Status: TERMINATED
-
Evaluation of Some Trace Elements in Follicular Fluid in ICSI Cases and Their Effect on ICSI Outcomes
NCT06719817 ·Status: RECRUITING
-
Polar Body Removal Before ICSI for Oocyte Activation in Previous Fertilization Failure Cases
NCT02913781 ·Status: COMPLETED ·Phase: NA
-
Development of a Screening Tool for Difficult Embryo Transfers
NCT05701072 ·Status: COMPLETED
-
Semen Processing for ICSI Using Swim-down and Density Gradient Methods
NCT02328534 ·Status: COMPLETED
-
Comparing HEPES-buffered With Bicarbonate-buffered as Handling Media During the ICSI Procedure on Live Birth Rate
NCT03778866 ·Status: COMPLETED ·Phase: NA
-
Influence of Ethnical Differences on the Egg Cell Collected in Patients Undergoing Fertility Treatment
NCT03927417 ·Status: COMPLETED
-
Prospective Sibling Oocyte Study of a New Method to Improve Embryo Development in IVF/ICSI Patients
NCT05680363 ·Status: COMPLETED ·Phase: NA
-
Oocyte Cryopreservation
NCT01232972 ·Status: TERMINATED ·Phase: NA
-
Evaluation of the Impact of Vitrification on Oocytes
NCT01223118 ·Status: COMPLETED ·Phase: NA