Effects of Dietary Folate and Phytate Zinc Absorption: Zinc Amino Acid Complexes vs. Zinc-chloride

NCT05273710 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2022-12-21

No results posted yet for this study

Summary

The purpose of this study is to determine the effects of consuming a small breakfast of juice and toast with added phytate or with taking a folic acid supplement on the absorption of a small amount of zinc that is either bound to amino acids or to chloride or picolinate. The results of this study will provide new information on how components of diet (e.g., phytate, and folic acid) affect the absorption of different forms of dietary zinc (e.g., zinc bound to amino acids, zinc chloride, and zinc picolinate).

Conditions

  • Dietary Zinc Absorption

Interventions

OTHER

Regular toast and juice

Participants consume a single test meal composed of regular whole wheat toast and apple juice, and zinc absorption is measured.

OTHER

High phytate toast and juice

Participants consume a single test meal composed of high phytate whole wheat toast and apple juice, and zinc absorption is measured.

OTHER

Regular toast and juice, with folic acid

Participants consume a single test meal composed of regular whole wheat toast and apple juice, with 400 mcg folic acid; and zinc absorption is measured.

Sponsors & Collaborators

Principal Investigators

  • Janet C King, Ph.D. · University of California, Berkeley

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
19 Years
Max Age
50 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-03-28
Primary Completion
2022-11-16
Completion
2022-11-16

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05273710 on ClinicalTrials.gov