Effects of Dietary Folate and Phytate Zinc Absorption: Zinc Amino Acid Complexes vs. Zinc-chloride
NCT05273710 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2022-12-21
Summary
The purpose of this study is to determine the effects of consuming a small breakfast of juice and toast with added phytate or with taking a folic acid supplement on the absorption of a small amount of zinc that is either bound to amino acids or to chloride or picolinate. The results of this study will provide new information on how components of diet (e.g., phytate, and folic acid) affect the absorption of different forms of dietary zinc (e.g., zinc bound to amino acids, zinc chloride, and zinc picolinate).
Conditions
- Dietary Zinc Absorption
Interventions
- OTHER
-
Regular toast and juice
Participants consume a single test meal composed of regular whole wheat toast and apple juice, and zinc absorption is measured.
- OTHER
-
High phytate toast and juice
Participants consume a single test meal composed of high phytate whole wheat toast and apple juice, and zinc absorption is measured.
- OTHER
-
Regular toast and juice, with folic acid
Participants consume a single test meal composed of regular whole wheat toast and apple juice, with 400 mcg folic acid; and zinc absorption is measured.
Sponsors & Collaborators
-
University of California, Berkeley
lead OTHER
Principal Investigators
-
Janet C King, Ph.D. · University of California, Berkeley
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 19 Years
- Max Age
- 50 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-03-28
- Primary Completion
- 2022-11-16
- Completion
- 2022-11-16
Countries
- United States
Study Locations
More Related Trials
-
Effects of Supplementation of Compound Nutrients on Plasma Homocysteine in Chinese Adults
NCT06363565 ·Status: RECRUITING ·Phase: NA
-
Effect of Zinc Supplementation on Hyperhomocysteinemia Compared to Folic Acid in CKD Patient on Hemodialysis
NCT06847139 ·Status: RECRUITING ·Phase: NA
-
Methionine Tolerance in Healthy Human Adults
NCT02566434 ·Status: COMPLETED ·Phase: NA
-
The Effect of Folic Acid Supplementation and Pregnancy on the Folate Forms in Red Blood Cells
NCT01741077 ·Status: COMPLETED
-
Measuring Erythrocyte Iron Incorporation From Different Dosing Regimens in Anemic Women
NCT03623997 ·Status: COMPLETED
-
Multi-micronutrient Supplementation During Peri-conception and Congenital Heart Disease
NCT02537392 ·Status: COMPLETED ·Phase: NA
-
Effects of Oral Supplementation With Creatine on Systemic Microvascular Endothelial Function in Vegetarian Individuals
NCT02961972 ·Status: COMPLETED ·Phase: NA
-
Effect of Betaine and Folic Acid on Vascular Function in Healthy Humans
NCT00102843 ·Status: COMPLETED ·Phase: NA
-
Effect of Phosphatidylcholine on Plasma Homocysteine in Healthy Volunteers
NCT00102232 ·Status: COMPLETED ·Phase: NA
-
Assessing Colonic Folate Absorption & Metabolism
NCT03421483 ·Status: UNKNOWN ·Phase: NA
-
Feasibility, Acceptability and Directional Signal Effect on Blood Folate Levels of Iodized Salt Fortified With Folic Acid: Clinical Study
NCT05935631 ·Status: COMPLETED ·Phase: NA
-
Optimizing Periconceptional and Prenatal Folic Acid Supplementation
NCT02300948 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of the Dietary Supplement SAMe on Blood Homocysteine Levels
NCT00284011 ·Status: COMPLETED ·Phase: NA
-
The Effects of 8-week Choline, Betaine, and Folic Acid Supplementation on Plasma Homocysteine Concentration During Guanidinoacetic Acid Loading in Young Healthy Volunteers
NCT01371357 ·Status: COMPLETED ·Phase: PHASE3
-
Influence of Iron and Foliate Transporters on Bioavailability of These Micronutrients in the Organism
NCT03438942 ·Status: COMPLETED ·Phase: NA
-
Supplementary Vitamin B12 Effects on Elevated Homocysteine Levels of Vegetarians - Clinical Trial
NCT01661309 ·Status: COMPLETED ·Phase: NA
-
Effect of Betaine, Serine and Folic Acid on Vascular Function in Healthy Volunteers
NCT00126347 ·Status: COMPLETED ·Phase: NA
-
Effect of Folic Acid on Primary Folate Forms in Relation to MTHFR
NCT01105351 ·Status: COMPLETED ·Phase: NA
-
Impact of High-dose Folic Acid Supplementation on Pathways Linked to DNA Formation
NCT01687127 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Folate Absorption Across the Large Intestine
NCT00941174 ·Status: COMPLETED ·Phase: PHASE1
-
Blood Folate and Homocysteine Levels Following Administration of Folic Acid According to Different Daily Dosing Schedules:a Simulation of Food Fortification
NCT00207558 ·Status: COMPLETED ·Phase: NA
-
The Optimization of Iron Bioavailability of Supplements Using Hepcidin Levels in Humans
NCT02050932 ·Status: COMPLETED ·Phase: NA
-
Bioavailability Study of Folic Acid in Healthy Women
NCT00709267 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 Status
NCT02679833 ·Status: COMPLETED ·Phase: NA
-
Effect of Vitamin C on Iron Absorption
NCT00570895 ·Status: COMPLETED ·Phase: NA