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Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 Status

NCT02679833 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 180

Last updated 2018-05-11

No results posted yet for this study

Summary

A 3 months randomized, placebo-controlled study on the effect of toothpaste fortified with vitamin B12 on vitamin B12 status markers and related metabolic markers. The primary outcome variable is the difference in the change of methylmalonic acid after 3 months between the two study arms.

Conditions

  • Cobalamin Deficiency

Interventions

DIETARY_SUPPLEMENT

Placebo

Toothpaste not containing the vitamin.

DIETARY_SUPPLEMENT

Cyanocobalamin

Toothpaste containing100 µg cyanocobalamin/g.

Sponsors & Collaborators

  • Institute of Alternative and Sustainable Nutrition (IFANE)

    collaborator UNKNOWN

  • Universität des Saarlandes

    lead OTHER

Principal Investigators

  • Markus Keller, PhD · Institute of Alternative and Sustainable Nutrition, Giessen, Germany

  • Rima Obeid, PhD · Saarland University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-11-30
Primary Completion
2015-12-31
Completion
2015-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02679833 on ClinicalTrials.gov