Effect of Betaine and Folic Acid on Vascular Function in Healthy Humans
NCT00102843 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2005-08-03
Summary
The purpose of this study is to determine whether lowering of fasting homocysteine concentrations improves vascular function in healthy volunteers, irrespective of the homocysteine-lowering agent.
Conditions
- Healthy
- Cardiovascular Diseases
Interventions
- PROCEDURE
-
supplementation with folic acid and betaine
Sponsors & Collaborators
-
Wageningen Centre for Food Sciences
lead OTHER
Principal Investigators
-
Petra Verhoef, PhD · Wageningen Centre for Food Sciences
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 50 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2002-10-31
- Completion
- 2003-06-30
Countries
- Netherlands
Study Locations
More Related Trials
-
Bioavailability of Folate From a Mixed Diet Using a Stable Isotope Method
NCT00130585 ·Status: COMPLETED ·Phase: NA
-
Effects of Supplementation of Compound Nutrients on Plasma Homocysteine in Chinese Adults With Hyperhomocysteinemia
NCT03720249 ·Status: UNKNOWN ·Phase: NA
-
Evaluating the Impact of B Vitamin Supplementation (Soloways™) on Homocysteine and LDL-C Levels in Patients With MTHFR, MTR, and MTRR Polymorphisms.
NCT06163443 ·Status: COMPLETED ·Phase: NA
-
Effects of Supplementation of Compound Nutrients on Plasma Homocysteine in Chinese Adults
NCT06363565 ·Status: RECRUITING ·Phase: NA
-
Blood Pressure Lowering Effect of B-vitamins in Adults With a Genetic Pre-disposition to Elevated Blood Pressure.
NCT04278378 ·Status: COMPLETED ·Phase: NA
-
Effect of Homocysteine-lowering Therapy With Folic Acid, Vitamin B12, and Vitamin B6 on Endothelium-dependent Vasodilatation of Forearm Resistance Vessels in Patients With Coronary Heart Disease
NCT00693589 ·Status: COMPLETED ·Phase: PHASE2
-
Bioavailability of Folic Acid Fortified Bread
NCT01570088 ·Status: COMPLETED ·Phase: PHASE2
-
Homocysteine and Progression of Atherosclerosis
NCT00005338 ·Status: COMPLETED
-
Natural Folate vs. Synthetic Folic Acid in Pregnancy
NCT04022135 ·Status: COMPLETED ·Phase: NA
-
Supplementary Vitamin B12 Effects on Elevated Homocysteine Levels of Vegetarians - Clinical Trial
NCT01661309 ·Status: COMPLETED ·Phase: NA
-
WENBIT - Western Norway B Vitamin Intervention Trial
NCT00354081 ·Status: COMPLETED ·Phase: PHASE3
-
The Effect of Folic Acid on Atherosclerosis, Cognitive Performance and Hearing
NCT00110604 ·Status: COMPLETED ·Phase: NA
-
Blood Pressure and Central Haemodynamics in Healthy Adults Stratified by MTHFR Genotype
NCT04948086 ·Status: COMPLETED
-
An Evaluation of Folic Acid to Improve Endothelial Sensitivity to Shear Stress in Seniors
NCT04016090 ·Status: COMPLETED ·Phase: NA
-
Vitamin B12 and Folate Administration on Homocysteine Concentrations After Nitrous Oxide Anesthesia
NCT00901394 ·Status: COMPLETED ·Phase: NA
-
Relative Bioavailability of Folic Acid and L-5-Methlytetrahydrofolate
NCT01584050 ·Status: COMPLETED ·Phase: NA
-
Where is the Initial Site of Biotransformation of Folates in Humans?
NCT02135393 ·Status: COMPLETED ·Phase: NA
-
Effect of Folic Acid Treatment in Coronary Artery Disease
NCT00300352 ·Status: UNKNOWN ·Phase: PHASE2
-
VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study)
NCT00056225 ·Status: COMPLETED ·Phase: PHASE3
-
Betaine METABOLISM OF PATIENTS With Homocystinuria
NCT02404337 ·Status: COMPLETED ·Phase: PHASE2
-
Relationship Between Folic Acid and Warfarin Metabolism and Effect
NCT00162409 ·Status: UNKNOWN ·Phase: NA
-
The Bread Trial: Effects of Bread Fortified With Folic Acid and Vitamin B12
NCT00353353 ·Status: COMPLETED ·Phase: NA
-
Effects of Oral Supplementation With Creatine on Systemic Microvascular Endothelial Function in Vegetarian Individuals
NCT02961972 ·Status: COMPLETED ·Phase: NA
-
Oral Vitamin B12 Supplementation and Cognitive Performance in Elderly People
NCT00111267 ·Status: COMPLETED ·Phase: NA
-
The Study of Relationship of Plasma Concentrations of Folic Acid, Vitamin B and Homocysteine With Carotid Atherosclerosis and Endothelium-Dependent Vasodilatation of Geriatric and Young Patients in the Ambulatory Care Department of NTUH
NCT00172250 ·Status: COMPLETED