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Ventilation Modes Effect on Intracranial Pressure During Laparoscopic Colectomy by Optic Nerve Sheath Diameter

NCT05268900 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 78

Last updated 2022-03-07

No results posted yet for this study

Summary

Patients who undergo laparoscopic surgery often experience increased intracranial pressure (ICP). In laparoscopic colectomy surgery, the duration always exceeds 2h with more liability to changes in arterial blood gases, hemodynamics, also the patient is in Trendelenburg position about 30° head down, Trendelenburg position is believed to create changes in hemodynamics, respiratory mechanics, metabolic response, and ICP as it affects vital organs especially if steep positioning. Various modes of mechanical ventilation have been experimented to achieve good intraoperative oxygenation which may cause changes in arterial blood gas values and hemodynamic parameters that might lead to changes in the ICP. In this study we will measure ONSD, basal, intraoperative, and in the PACU to evaluate the effect of different ventilation modes (both VCV mode and PCV-VG mode) on intracranial pressure.

Conditions

  • Laparoscopic Colectomy

Interventions

DEVICE

Volume control ventilation group

Volume control ventilation mode

DEVICE

Pressure control ventilation-volume guaranteed group

Pressure control ventilation-volume guaranteed mode

Sponsors & Collaborators

  • Mansoura University

    lead OTHER

Principal Investigators

  • Hanaa M El Bendary · Assistant professor, MD anesthesia Department, Faculty of Medicine,

  • Doaa G Diab · professor, MD anesthesia Department, Faculty of Medicine, Mansoura University, Egypt

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-30
Primary Completion
2023-03-31
Completion
2023-04-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05268900 on ClinicalTrials.gov