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Intraoperative PEEP Setting During Laparoscopic Gynecologic Surgery

NCT03256396 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2019-08-22

No results posted yet for this study

Summary

The creation of pneumoperitoneum during laparoscopic surgery can have significant effects on the respiratory system including decreased respiratory system compliance, decreased vital capacity and functional residual capacity and atelectasis formation. Intraoperative mechanical ventilation, especially setting of positive end-expiratory pressure (PEEP) has an important role in respiratory management during laparoscopic surgery. The aim of this study is to determine whether setting of PEEP guided by measurement of pleural pressure would improve oxygenation and respiratory system compliance during laparoscopic surgery.

Conditions

  • Positive-Pressure Respiration/Methods
  • Esophagus/Physiopathology
  • Pleura/Physiopathology
  • Gynecologic Surgical Procedures
  • Laparoscopy
  • Humans
  • Female

Interventions

PROCEDURE

PEEP setting based on esophageal pressure measured

PEEP is set on the basis of esophageal pressure measurement with the aim to maintain transpulmonary pressure during expiration between 0 and 5 cmH2O

Sponsors & Collaborators

  • Mahidol University

    lead OTHER

Principal Investigators

  • Annop Piriyapatsom, MD · Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-03-30
Primary Completion
2018-06-29
Completion
2018-12-28

Countries

  • Thailand

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03256396 on ClinicalTrials.gov