Impact of the Genetic Polymorphism on COVID-19 in Egypt

NCT05157217 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 98

Last updated 2022-07-27

No results posted yet for this study

Summary

The COVID-19 infection severity depends on many factors, including genetic factors. The SNPs of ACE1, ACE2 and TMPRSS2; which have a big role in the viral entry to the cells, will be tested and help establish a relationship between the genetic variation in these SNPs and the severity of the COVID-19 symptoms. The aim of this study is to detect the association between ACE1, ACE2 and TMPRSS2 gene polymorphism variants and occurrences of severe complications in Egyptians patients with COVID-19 disease.

Conditions

Sponsors & Collaborators

  • Misr International University

    collaborator OTHER
  • Cairo University

    lead OTHER

Principal Investigators

  • Naglaa S Bazan, PhD · Cairo University

  • Khaled Farouk, MD · Cairo University

  • Adel RA Abdallah, PhD · Al-Azhar University in Cairo

  • Abdelrahman A Abdelgawad, BScPharm · Misr International University

  • Neven MA Sarhan, PhD · Misr International University

  • Raed SA Ismail, PhD · Al-Azhar University in Cairo

  • Mohamed GL El-Ansary, MD · Cairo University

  • Mona Schaalan, PhD · Misr International University

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-12-15
Primary Completion
2022-08-15
Completion
2022-09-15

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05157217 on ClinicalTrials.gov