Investigation of the Gut Microbiota in Acute Myeloid Leukemia Receiving Two Different Induction Therapies
NCT05123352 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2021-11-17
Summary
In this observational single-center cohort study, metagenomic Next-Generation Sequencing (mNGS) will be used to investigate the features and changes of gut microbiota in acute myeloid leukemia (AML) patients during the treatment of two different induction therapy regimens \[standard intensive chemotherapy (7+3) or bcl-2 inhibitor-based targeted therapy\].
Conditions
- Acute Myeloid Leukemia
- Adult
- Gut Microbiota
- Infections
Interventions
- OTHER
-
collection of biological samples and clinical data
blood and feces samples
Sponsors & Collaborators
-
The First Affiliated Hospital of Soochow University
lead OTHER
Principal Investigators
-
Suning Chen, professor · The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-11-30
- Primary Completion
- 2022-06-30
- Completion
- 2022-11-30
Countries
- China
Study Locations
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