Establishment of Individualized Immunotherapy Strategy and Platform Based on Changes of Intestinal Microbiota

The Gut Microbiome and Immunotherapy Response in Solid Cancers

NCT06050733 ·Status: RECRUITING

Tumor Immunotherapy and Microbiome Analysis

NCT04579978 ·Status: UNKNOWN

Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer

NCT06613165 ·Status: RECRUITING

The Mechanism of Enhancing the Anti-tumor Effects of CAR-T on PC by Gut Microbiota Regulation

NCT04203459 ·Status: UNKNOWN

High-activity Natural Killer Immunotherapy for Small Metastases of Colorectal Cancer

NCT03008499 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal Tumors

NCT05515796 ·Status: COMPLETED ·Phase: PHASE2

Anti-PD-1 Antibody Combined With Autologous DC and NK Cells in the Treatment of Digestive Carcinoma

NCT05461235 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2

Evolution of Proteomic Profiles of Intestinal Microbiota in Patients With Locally Advanced or Metastatic Urothelial Carcinomas

NCT04566029 ·Status: COMPLETED

Neoantigen-based Peptide Vaccine and Conventional Third-line Therapy for CRC Progressed After Second-line Treatment

NCT06751966 ·Status: RECRUITING ·Phase: NA

Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal Cancer

NCT05215379 ·Status: COMPLETED ·Phase: PHASE2/PHASE3

Induction Chemotherapy Combined With Neoadjuvant Immunotherapy for MSS Colon Cancer

NCT05914389 ·Status: RECRUITING ·Phase: PHASE2

Clinical Trial to Evaluate the Safety and Efficacy of IM96 CAR-T Cells Therapy in Patients With Advanced Digestive System Neoplasms

NCT05287165 ·Status: UNKNOWN ·Phase: EARLY_PHASE1

Predictive Factors for Outcomes of Fruquintinib Plus Immunotherapy in Colorectal Cancer

NCT05635149 ·Status: UNKNOWN

Multi-omics Model Predicts Efficacy of Preoperative Neoadjuvant Chemoradiotherapy Combined PD-1 Antibody Therapy for Locally Advanced Rectal Cancer

NCT05368051 ·Status: UNKNOWN

Fecal Microbiota Transplantation in Patients With Malignancies Not Responding to Cancer Immunotherapy

NCT05273255 ·Status: COMPLETED ·Phase: NA

Multicenter Retrospective Study on Optimizing Combination Immunotherapy Strategies in MSS/MSI-L/pMMR Advanced Colorectal Cancer

NCT06849362 ·Status: ENROLLING_BY_INVITATION

IMC001 for Clinical Research on Advanced Digestive System Malignancies

NCT05028933 ·Status: RECRUITING ·Phase: PHASE1

Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid Tumors

NCT05538195 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2

Neoantigen-based Peptide Vaccine and Conventional Second-line Therapy for CRC Progressed After First-line Treatment

NCT06751914 ·Status: RECRUITING ·Phase: NA

Clinical Outcomes of Treatment With Immunomodulator Plus Cancer Therapies for Patients With Colorectal Cancer

NCT06557668 ·Status: RECRUITING

Role of Gut Microbiota in Neoadjuvant Radioimmunotherapy for MSS, Locally Advanced Rectal Cancer

NCT06898359 ·Status: COMPLETED

Exploring the Predictive Effect of Intestinal and Oral Microbiota on the Efficacy of Neoadjuvant Radiotherapy and Chemotherapy for Locally Advanced Rectal Cancer Based on Machine Learning

NCT07346729 ·Status: COMPLETED

Study of Association Between Peripheral Immune Cells and Recurrence in Stage II/III Colorectal Cancer

NCT01911988 ·Status: UNKNOWN

Association Between the Composition of the Intestinal Microbiota and Tumor Response in Locally Advanced Rectal Cancer

NCT06181201 ·Status: TERMINATED

Correlation Between Gut Microbiota and Clinical Response to CAR-T Treatment for Hematological Malignancies

NCT06041815 ·Status: UNKNOWN