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Gut Microbiota and Metabonomics

NCT05205187 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 450

Last updated 2022-01-25

No results posted yet for this study

Summary

To evaluate the correlation between gut microbiota and metabolites in Borrmann type IV gastric cancer; To find the effects of microflora and metabolites on target organs; To detect the mechanism of key flora and metabolite by in vitro and in vivo experiments; To construct models of gut microbiota and metabonomics by machine learning.

Conditions

  • Stomach Neoplasms
  • Gut Microbiota
  • Metabolomics

Interventions

PROCEDURE

Healthy control specimen collection

Collecting blood and feces from healthy population.

PROCEDURE

Non-Borrmann IV patient specimen collection

Collecting blood, feces and gastric cancer tissues from Non-Borrmann IV patients.

PROCEDURE

Borrmann IV patient specimen collection

Collecting blood, feces and gastric cancer tissues from Borrmann IV patients.

Sponsors & Collaborators

  • Liaoning Cancer Hospital & Institute

    collaborator OTHER

  • The Second Hospital of Shandong University

    collaborator OTHER

  • The General Hospital of Fushun Mining Bureau

    collaborator UNKNOWN

  • The fourth People's Hospital of Changzhou

    collaborator UNKNOWN

  • The First People's Hospital of Jingzhou

    collaborator OTHER

  • First Hospital of China Medical University

    lead OTHER

Principal Investigators

  • Kai Li, MD · First Hospital of China Medical University

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-02-28
Primary Completion
2024-01-01
Completion
2025-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05205187 on ClinicalTrials.gov