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Fecal Microbiota Transplantation for Radiation Enteritis

NCT03516461 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2025-03-30

No results posted yet for this study

Summary

Radiation enteritis is one of the most feared complications after abdominal or pelvic radiation therapy.The gut microbiota is considered to constitute a "microbial organ" which has pivotal roles in the intestinal diseases and body metabolism. Evidence from animal studies demonstrated the link between intestinal bacteria and radiation enteritis. This clinical trial aims to evaluate the efficacy and safety of fecal microbiota transplantation (FMT) for radiation enteritis.

Conditions

  • Radiation Enteritis

Interventions

PROCEDURE

Fecal Microbiota Transplantation (FMT)

Fecal microbiota transplantation for patients via nasointestinal tube or gastroscopy or colonic TET tube

Sponsors & Collaborators

  • Jiangxi Provincial Cancer Hospital

    collaborator OTHER

  • The Second Hospital of Nanjing Medical University

    lead OTHER

Principal Investigators

  • Faming Zhang, MD; PHD · The Second Hospital of Nanjing Medical University

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-07
Primary Completion
2025-07-01
Completion
2025-07-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03516461 on ClinicalTrials.gov